2020 NEWS

Company news



New website released

The new website of Cube Pharma & Nutrition has been completed and released. We are really happy that this new portal of information and communication is open to everyone who wants to learn about our company, our products and in general our company's approach to every day health issues that concern all of us. Currently the website is in English and soon the Greek version shall as well be available, stay tuned!

Product news



BioGaia’s oral health probiotic L. reuteri Prodentis reduces bleeding of the gums


A randomised, double-blind, placebo-controlled trial in healthy sailors showed that supplementation of L. reuteri Prodentis significantly reduced bleeding of the gums compared to placebo. The study was published online 4 February 2020 in Journal of Periodontology (https://doi.org/10.1002/JPER.19-0393). “Supplementation with lozenges containing L. reuteri is an effective and easy way to maintain or improve periodontal health in healthy individuals with limited oral hygiene routines”, says principal investigator of the study, Professor Ulrich Schlagenhauf, Department of Periodontology at the University Hospital Würzburg in Germany.

72 healthy sailors were randomised to either two lozenges daily (4x10^8 CFU/day) of L. reuteri Prodentis (L. reuteri ATCC PTA 5289 and L. reuteri DSM 17938) or an equivalent placebo for 42 days. The intervention took place when the sailors attended a six-week military practicing mission at sea and was not combined with professional cleaning of the mouth or oral hygiene instructions.

Primary outcome of the study was bleeding of the gums, but also plaque and pocket depth as well as other parameters, were assessed.

Less bleeding with L. reuteri Prodentis

In the probiotic group all assessed parameters were significantly improved compared to baseline and to the placebo group both at day 14 and day 42. In the placebo group, on the other hand, all parameters showed a significant deterioration at the end of the study.

“Based on our study results, we can conclude that supplementation of L. reuteri-lozenges offers new therapeutic and preventive options in individuals with gingivitis”, says Professor Schlagenhauf.


New names for probiotics within the Lactobacillus genus


Last week new names for probiotics belonging to the genus Lactobacillus was adopted. As a result many of the most well-known commercial probiotics have been given new genus names, including BioGaia’s, which is now called Limosilactobacillus reuteri.

The first Lactobacillus species was named in 1901. In the last decades new analytical tools have enabled scientists to discover many new species as well as realizing that the species historically grouped under Lactobacillus were too different from each other. To keep the probiotic groups accurate and organized, the genus Lactobacillus was therefore split into 25 different genera. As a result, many probiotics have been given new genus names.

A probiotic name consists of a genus, a species and a strain name. It is only the genus part, Lactobacillus, that has now been changed. Species and strain names remain the same, and of course, the organisms themselves, including their effects and safety.

New name – same probiotic

For consumers the change will be noticed on the package label or in the accompanying product information. The content of the probiotic is exactly the same as before.

The article describing the new taxonomy was published in International Journal of Systematic and Evolutionary Microbiology (IJSEM). The paper includes a complete overview of all new names as well as a link to a tool that allows you to check the conversion ‘old’ to ‘new’ or vice versa.

A full transition from old to new nomenclature will take time, probably years. BioGaia has a plan for transition and implementation both digitally and in print.

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for YOU 

We are...you!


With this in mind, we were created.

Because you do it best when you 

know the problems from inside, whether this means as a company or


"The story behind Cube"

E. Kalofolias

Co-founder and Managing Director

Our logo 
"The story behind oxymoron"

A sphere and a cube. A circle and

a square. A coincidence or a true

and deeper meaning?



We do want to offer to you as much information as possible about how we do it and why we do it. Offer to you the deep knowledge of what does every product offer and why it offers 

what promises, how it works, why it 

works better and if you have any questions we are here to give you all the answers. 

Because we want you to be sure that 

what you use is the best possible solution for you and your family!

our most recent news

Company news

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Events & congresses


New website released

The new website of Cube Pharma & Nutrition has been completed and released

Read more


New Agreement

Cube and BioGaia futher expand their collaboaration for the promotion of the patented and world's most studied oral health probiotic, BioGaia Prodentis.

Read more


Currently, due to Covid-19 safety measures, all congresses and exhibitions have been postponed